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AZD-6244
Purity > 98.0 %
| CAS Number: |
606143-52-6
|
| Chemical Formula: |
C17H15BrClFN4O3
|
| Molecular Weight: |
457.68 g/mol
|
AZD-6244 (ARRY-142886) is an orally active, highly specific inhibitor of MEK that has shown tumor-suppressive activity in a wide range of preclinical models of human cancer. AZD-6244 is currently in phase II development for the treatment of melanoma, non-small cell lung and pancreatic cancer.
ARRY-142886 is a potent and selective MEK1/2 inhibitorthat is highly active in both in vitro and in vivo tumor models.This compound is currently being investigated in clinical studies.
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