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AZD-1480 5 mg

Price:
$150.00
SKU:
GB-A0113-5MG
Quantity:

AZD-1480

Purity > 99.0 %

  CAS Number   935666-88-9
  Chemical Formula:   C14H14ClFN8
  Molecular Weight:
  348.77 g/mol

 

AZD1480 is a potent, competitive small-molecule inhibitor of JAK1/2 kinase, and that it is capable of inhibiting STAT3 phosphorylation and tumor growth in a STAT3-dependent manner. AZD1480 inhibits tumor angiogenesis and metastasis in part by affecting the tumor microenvironment.

AZD-1480 is a potent JAK2 inhibitor (IC50 = 260 pM)

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