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Anti-NF200 Monoclonal
| Clone | NF-200 |
| Size | 100μg/vial |
| Form | lyophilized |
| Ig type | mouse IgG1 |
| Immunogen | C-terminal segment of enzymatically dephosphorylated pig Neurofilament 200. |
| Application | WB; IHC-P; IHC-F |
| Cross Reactivity | Human, mouse, rat. |
| Reconstitution | 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, |
| the antibody concentration will be 100μg/ml. | |
| Storage | At -20˚C for one year. After reconstitution, at 4˚C for one month. |
| It can also be aliquotted and stored frozen at -20˚C for a longer time. | |
| Avoid repeated freezing and thawing. | |
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Neurofilaments are composed of 3 neuron-specific proteins with apparent molecular masses of 68 kD (NFL), 125 kD (NFM), and 200 kD (NFH) on SDS-gel electrophoresis. Genomic clones for the largest human neurofilament protein (NF-H) were isolated, the intron/exon boundaries mapped and the entire protein-coding regions (exons) sequenced. mutations in neurofilaments have been linked to some forms of Charcot-Marie-Tooth disease (CMT). |
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