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Anti-NF68 Monoclonal 100ug

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Anti-NF68 Monoclonal

Clone NF-68
Size  100μg/vial
Form lyophilized
Ig type mouse IgG1
Immunogen Pig spinal cord.
Application WB; IHC-P; IHC-F
Cross Reactivity Human, pig, rat
Reconstitution 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used,
  the antibody concentration will be 100μg/ml.
Storage At -20˚C for one year. After reconstitution, at 4˚C for one month. 
             It can also be aliquotted and stored frozen at -20˚C for a longer time. 
  Avoid repeated freezing and thawing.

Neurofilaments are composed of 3 neuron-specific proteins with apparent molecular masses of 68 kD (NFL), 125 kD (NFM) and 200 kD (NFH) on SDS-gel electrophoresis. And they have a role in the maturation of regenerating myelinated axons. Neurofilament 68 (NF68), also called Neurofilament Protein, Light Chain (NFL). It is one of the most abundant cytoskeletal components of the neuron. Mutations in this gene were reported as a cause for autosomal dominant Charcot-Marie-Tooth type 2E (CMT2E) linked to chromosome 8p21. NFL was identified repeatedly in both screenings and found to interact with Myotubularin-related 2 gene, MTMR2 in both Schwann cells and neurons.

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