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Anti-HSP70 Monoclonal 100ug

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Anti-HSP70 Monoclonal

Clone SJ-70
Size  100μg/vial
Form lyophilized
Ig type mouse IgG1
Immunogen HSP70 isolated from bovine brain.
Application WB; IHC-P; IHC-F
Cross Reactivity Human.
Reconstitution 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used.  
  The antibody concentration will be 100μg/ml.
Storage At -20˚C for one year. After reconstitution, at 4˚C for one month. 
             It can also be aliquotted and stored frozen at -20˚C for a longer time. 
  Avoid repeated freezing and thawing.

Heat-shock proteins, or stress proteins, are expressed in response to heat shock and a variety of other stress stimuli including oxidative free radicals and toxic metal ions. Sargent et al. (1989) identified a duplicated HSP70 locus in the class III region of the major histocompatibility complex on 6p21.3. A duplicated locus encoding the major heat shock-induced protein HSP70 is located in the major histocompatibility complex (MHC) class III region 92 kilobases (kb) telomeric to the C2 gene. The 70-kd mammalian heat shock proteins are structurally and functionally related to the uncoating protein that releases clathrin triskelia from coated vesicles.

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