(SH3P2, OSF, OSTF-1, Osteoclast-stimulating factor 1, OSTF1, FLJ20559, bA235O14.1.)
OSTF1 is an intracellular protein produced by osteoclasts that induces bone resorption, via signaling cascade which results in the secretion of factors enhancing osteoclast formation and activity.
OSTF1 Human Recombinant produced in E.Coli is a monomeric, non-glycosylated, polypeptide chain containing 222 amino acids (1-214) and having a molecular mass of 25.1 kDa. The OSTF1 is fused to 8 amino acid His Tag at C-terminus & purified by proprietary chromatographic techniques.
Purity: Greater than 95.0% as determined by SDS-PAGE.
Source: Escherichia Coli.
Physical Appearance: Sterile Filtered colorless solution.
Formulation: OSTF1 protein solution contains 20mM Tris buffer pH=8, 0.5mM DTT and 10% glycerol.
Amino acid sequence:
MSKPPPKPVK PGEGGQVKVF RALYTFEPRT PDELYFEEGD IIYITDMSDT NWWKGTSKGR TGLIPSNYVA EQAESIDNPL HEAAKRGNLSWLRECLDNRV GVNGLDKAGS TALYWACHGG HKDIVEMLFT QPNIELNQQN KLGDTALHAA AWKGYADIVQ LFLAKGARTD LRNIEKKLAF DMATNAACAS LLKKKQGTDA VRTLSNAEDY LDDEDSDLEH HHHHH.
Storage:
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles.
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