Purity > 99.0 %
CAS Number: |
761439-42-3
|
Chemical Formula: |
C30H40ClN7O3S
|
Molecular Weight: |
614.2 g/mol
|
A selective NPM-ALK inhibitor with IC50 values between 2 and 10 nM. NVP-TAE-684 treatment resulted in a rapid and sustained inhibition of phosphorylation of NPM-ALK and its downstream effectors and subsequent induction of apoptosis and cell cycle arrest in cancer cells.
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