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NVP-TAE-684 5 mg



Purity > 99.0 %

  CAS Number:
  Chemical Formula:
  Molecular Weight:
  614.2 g/mol


A selective NPM-ALK inhibitor with IC50 values between 2 and 10 nM. NVP-TAE-684 treatment resulted in a rapid and sustained inhibition of phosphorylation of NPM-ALK and its downstream effectors and subsequent induction of apoptosis and cell cycle arrest in cancer cells.

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