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Mevastatin 5 mg



(Compactin; (1S,7S,8S,8aR)-8-{2-[(2R,4S)-4-Hydroxytetrahydro-2H-pyran-2-yl]ethyl}-7-methyl-1,2,3,7,8,8a-hexahydro-1-naphthalenyl (2S)-2-methylbutanoate)

Purity >98.0%

  CAS Number:
  Chemical Formula:
  Molecular Weight:
  390.51 g/mol


Mevastatin is a statin agent which inhibits the HMG-CoA reductase in susceptible bacterial strains, thus affects the the biosynthesis of essential cholesterols.

Mevastatin is an antibiotic shown to cause apoptosis, apparently by inhibiting post-translational prenylation of proteins such as Ras. Similarly, mevastatin increases eNOS mRNA and protein levels by blocking the geranylgeranylation of Rho GTPase.

Appearance: White powder

Store: 2-8°C

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  Toronto Research Chemicals    M340500100MG

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