FGF7/KGF1, Murine

(Recombinant Murine Fibroblast Growth Factor 7, FGF7, KGF1, Keratinocyte Growth Factor 1)

Purity: >96% by SDS-PAGE and HPLC analyses

Source: Escherichia coli

FGF7/KGF1 is a member of the Fibroblast Growth Factor family of proteins. In the FGF family, FGF7 is most closely related to FGF10 (KGF2), FGF3 and FGF22.

Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation.

FGF7/KGF1 is mitogen factor specific for epithelial cells and keratinocytes and signals through Fibroblast Growth Factor Receptor-2b (FGFR-2b) and plays an important role in kidney and lung development, angiogenesis and wound healing.

rMuFGF7/KGF1 General Information
Amino Acid Sequence (164 aa):
MCNDMSPEQT ATSVNCSSPE RHTRSYDYME GGDIRVRRLF CRTQWYLRID KRGKVKGTQE MKNSYNIMEI RTVAVGIVAI KGVESEYYLA MNKEGKLYAK KECNEDCNFK ELILENHYNT YASAKWTHSG GEMFVALNQK GIPVKGKKTK KEQKTAHFLP MAIT

Reconstitution:
The sample should be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in aqueous buffer containing 0.1% BSA to a concentration of 0.1 - 1.0 mg/mL. Reconstituted solutions are stable for up to one week at 2 - 8°C. Stock solutions should be aliquoted and stored at - 80°C. Further dilutions should be made in appropriate buffered solutions containing BSA or serum, and 1 μg/ml heparin sulfate.

Storage:
The lyophilized sample is stable at 2-8°C, but should be kept desiccated at -20°C for long term storage. The reconstituted sample can be apportioned into working aliquots and stored at -80°C for maximal stability. Avoid repeated freeze/thaw cycles.

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