TGF b 3, Mouse

(Transforming Growth Factor-beta3, TGFB3, ARVD, FLJ16571, TGF-beta3.)

Transforming growth factor betas (TGF Betas) mediate many cell-cell interactions that occur during embryonic development. Three TGF Betas have been identified in mammals. TGF Beta 1, TGF Beta 2 and TGF Beta 3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecule.

TGF-b3 Mouse Recombinant produced in E.Coli is a disulfide-linked homodimeric, non-glycosylated, polypeptide chain containing 112 amino acids and having a molecular mass of 25,445 Dalton. The TGF-b 3 is purified by standard chromatographic techniques.

Purity: Greater than 98.0% as determined by SDS-PAGE.

Source: Escherichia Coli.

Physical Appearance: Sterile Filtered clear solution.

Formulation: The Mouse TGFB3 protein solution contains 20% Ethanol and 0.12% Acetic acid.

TGF b 3 General Information

Amino acid sequence:
The sequence of the first five N-terminal amino acids was determined and was found to be Ala-Leu-Asp-Thr-Asn.

Storage:
Mouse TGF-beta 3 although stable at room temperature for 3 weeks, should be stored at 4°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).

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