Purity >98.0%
CAS Number: |
28643-80-3
|
Chemical Formula: |
C40H67NaO11
|
Molecular Weight: |
746.94 g/mol
|
Nigericin is a polycyclic ether carboxylic acid originally isolated from Streptomyces hygroscopicus. Nigericin acts as an H+, K+, Pb2+ ionophore. Most commonly it is an antiporter of H+ and K+. In the past nigericin was used as an antibiotic active against gram positive bacteria.
Nigericin inhibits the Golgi functions in Eukaryotic cells. Nigericin exhibits anti-HIV activity.
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