(Interleukin-28B, IL-28B, Cytokine Zcyto22, Interferon lambda-3, IFN-lambda-3, Interferon lambda-4, IFN-lambda-4, Interleukin-28C, IL-28C, IL28B, IFNL3, IFNL4, IL28C, ZCYTO22.)
IL-28B is a cytokine remotely related to type I interferons and the IL-10 family. Interleukin-28B, interleukin 28A (IL28A), and interleukin 29 (IL29) are 3 closely related cytokine genes which form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by these 3 genes can be induced by viral infection. All 3 cytokines interact with a heterodimeric class II cytokine receptor which consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).
Interleukin-28B Human Recombinant produced in HEK cells is a non-glycosylated monomer, having a total molecular weight of 24kDa. The IL28B is purified by proprietary chromatographic techniques.
Purity: Greater than 95% as obsereved by SDS-PAGE.
Source: HEK.
Physical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation: The IL28B was lyophilized from 1mg/ml in 1xPBS.
Storage:
Lyophilized IL-28B although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IL28B should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
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