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Fosfomycin Sodium 25 g


Fosfomycin Sodium

  CAS Number:
  Chemical Formula:
  Molecular Weight:
  182.02 g/mol


Fosfomycin (also known as Phosphomycin or Phosphonomycin) is a phosphonic acid derivative antibiotic originally isolated from certain Streptomyces species. Fosfomycin can be re-merge as a new potential good candiate for antibiotic resistance if toxicity can be surpassed.

Fosfomycin inhibits bacterial cell wall biogenesis by inactivating the enzyme UDP-N-actetylglucosamine-3-enolpyruvyltransferase, also known as MurA. This enzyme catalyzes the committed step in peptidoglycan biosynthesis, namely the ligation of phosphoenolpyruvate (PEP) to the 3'-hydroxyl group of UDP-N-acetylglucosamine.

Gram-positive bacteria such as Staphylococcus aureus and Staphylococcus epidermidis. gram-negative bacteria including Escherichia coli.

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