FGF8, Murine

(Recombinant Murine Fibroblast Growth Factor 8, FGF8, AIGF)

Purity: >97% by SDS-PAGE and HPLC analyses

Source: Escherichia coli

FGF8 is a member of the Fibroblast Growth Factor family of proteins. These proteins play a crucial role during prenatal development and postnatal growth. In mice, there are 8 known alternate spliced forms of FGF8: FGF8A-H. The human and murine FGF8A and B proteins are 100% identical while FGF8E and F proteins are 98% identical between human and mouse. FGF8 targets mammary carcinoma cells and other cells expressing the FGF receptors. In the FGF family, FGF8 is most closely associated with FGF17 and FGF18.

rMuFGF8 General Information
Amino Acid Sequence (246 aa):
QVRSAAQKRG PGAGNPADTL GQGHEDRPFG QRSRAGKNFT NPAPNYPEEG SKEQRDSVLP KVTQRHVREQ SLVTDQLSRR LIRTYQLYSR TSGKHVQVLA NKRINAMAED GDPFAKLIVE TDTFGSRVRV RGAETGLYIC MNKKGKLIAK SNGKGKDCVF TEIVLENNYT ALQNAKYEGW YMAFTRKGRP RKGSKTRQHQ REVHFMKRLP RGHHTTEQSL RFEFLNYPPF TRSLRGSQRT WAPEPR

Reconstitution:
The sample should be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in aqueous buffer containing 0.1% BSA to a concentration of 0.1 - 1.0 mg/mL. Reconstituted solutions are stable for up to one week at 2 - 8°C. Stock solutions should be aliquoted and stored at - 80°C. Further dilutions should be made in appropriate buffered solutions containing BSA or serum, and 1 μg/ml heparin sulfate.

Storage:
The lyophilized sample is stable at 2-8°C, but should be kept desiccated at -20°C for long term storage. The reconstituted sample can be apportioned into working aliquots and stored at -80°C for maximal stability. Avoid repeated freeze/thaw cycles.

Free Shipping within the Continental USA