(Fibroblast Growth Factor 15, FGF19.)
FGF-15 takes part in the suppression of bile acid biosynthesis by down-regulation of CYP7A1 expression. FGF-15 is expressed in the developing brain.
FGF-15 Protein is 23.78 kDa protein containing 203 amino acid residues including a 10 a.a. N-Terminal His-tag.
Source: E. coli
Physical Appearance: Filtered White lyophilized (freeze-dried) powder.
Formulation: FGF-15 was filtered (0.4µm) and lyophilized from 0.5 mg/ml supplied in 20mM TRIS and 20mM NaCl, pH 8.0.
Amino Acid Sequence:
MKHHHHHHAS RPLAQQSQSV SDEDPLFLYG WGKITRLQYL YSAGPYVSNC FLRIRSDGSV DCEEDQNERN LLEFRAVALK TIAIKDVSSV RYLCMSADGK IYGLIRYSEE DCTFREEMDC LGYNQYRSMK HHLHIIFIQA KPREQLQDQK PSNFIPVFHR SFFETGDQLR SKMFSLPLES DSMDPFRMVE DVDHLVKSPS FQK.
Applications:
Western blotting
Storage:
Store lyophilized FGF-15 at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted FGF-15 can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C.
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