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EGF, Rat 20 ug


EGF, Rat

(Recombinant Rat Epidermal Growth Factor, EGF, HMGF (Human Milk Growth Factor), PGF (Prostatic Growth Factor))

Purity: >97% by SDS-PAGE and HPLC analyses

Source: Escherichia coli

EGF (Epidermal Growth Factor) is a family of growth factors that are derived from membrane-anchored precursors.

The family is characterized by the presence of at least one “EGF-like domain” (characterized by the presence of three disulfide bonds, formed from 6 conserved cysteine residues) in their extracellular domain. EGF was originally discovered as an activity that induced early eyelid opening, incisor eruption, hair growth inhibition, and stunting of growth when injected into newborn mice.

Additionally, EGF has been shown to inhibit gastric secretion, is involved in wound healing and signals through a receptor known as c-erbB (a class I tyrosine kinase receptor).

rRtEGF General Information
Amino Acid Sequence (54 aa):

The sample should be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Reconstituted solutions are stable for up to one week at 2-8°C. Stock solutions should be aliquoted and stored at -80°C. Further dilutions should be made in appropriate buffered solutions.

The lyophilized sample is stable at 2-8°C, but should be kept desiccated at -20°C for long term storage. The reconstituted sample can be apportioned into working aliquots and stored at -80°C for maximal stability. Avoid repeated freeze/thaw cycles.

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