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Cyclosporin A 25 mg


Cyclosporin A

(Antibiotic S 7481F1; Cyclosporine)

Purity > 99.0 %

  CAS Number:
  Chemical Formula:
  Molecular Weight:
  1202.63 g/mol


Cyclosporin A is a fungal metabolite possessing potent immunosuppressive properties. This antibiotic has the ability to inhibit the T-cell receptor signal transduction pathway via the formation of cyclosporin A−cyclophilin complex that inhibits calcineurin (protein phosphatase 2B). Inhibits nitric oxide synthesis induced by interleukin 1α, lipopolysaccharides and TNFα and can block cytochrome c release from mitochondria.

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  Toronto Research Chemicals    C9889001G
  US Pharmacopeia    1158504

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