(Antibiotic S 7481F1; Cyclosporine)
Purity > 99.0 %
CAS Number: |
59865-13-3
|
Chemical Formula: |
C62H111N11O12
|
Molecular Weight: |
1202.63 g/mol
|
Cyclosporin A is a fungal metabolite possessing potent immunosuppressive properties. This antibiotic has the ability to inhibit the T-cell receptor signal transduction pathway via the formation of cyclosporin A−cyclophilin complex that inhibits calcineurin (protein phosphatase 2B). Inhibits nitric oxide synthesis induced by interleukin 1α, lipopolysaccharides and TNFα and can block cytochrome c release from mitochondria.
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Alfa Aesar | J63191-03 |
Alfa Aesar | J63191-06 |
Amresco | K978-1L |
Amresco | 1101/100 |
Amresco | K983-100MG |
Amresco | K978-4L |
EMD Millipore | 239835-100MG |
TCI America | C2408-1G |
TCI America | C2408-100MG |
Toronto Research Chemicals | C9889001G |
US Pharmacopeia | 1158504 |