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(-)-Cotinine 250mg




Purity > 98.0%

  CAS Number:   486-56-6
  Chemical Formula:   C10H12N2O
  Molecular Weight:  176.22 g/mol


Melting point: 34-39°

Boiling point: 145-147°/3mm

Flash point: >110°(230°F)

Solubility: Not miscible or difficult to mix in water. Soluble in dimethyl sulfoxide (100 mM), ethanol (50 mg/ml, yielding a clear, faint yellow to yellow solution), methanol and chloroform.


(-)-Cotinine is used to activate a subpopulation of α3/ α6β2 nAChRs in monkey striatum. It binds nicotinic- and muscarinic-type acetylcholine receptors with minimal receptor desensitization and demonstrates antipsychotic drug-like properties in behavioral models, neuroprotective properties in neurodegenerative disease models, and enhances attention in a delayed matching-to-sample task.


Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature is 2 - 8°C.

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