CD4, Human (203-317 a.a.)

(gp55, HLA-2, L3 / T4, Ly-4, T cell antigen T4/LEU3, T4, sCD4.)

CD4, a single chain transmembrane glycoprotein, is found on a T cell subset (helper/inducer) representing 45% of peripheral blood lymphocytes. It is also present on 80% of thymocytes and at a lower level on monocytes. It is involved in recognition of antigen presented along with MHC class II by APCs. It serves as receptor for HIV. Antibody to CD4 recognizes T-helper cells required for recognition of class II antigens. It reacts with ~60% of peripheral blood E rosette-positive (E+) cells while showing negligible reactivity with E- cells, monocytes, granulocytes, EBV-transformed B cell lines, and mouse splenocytes.

CD-4 Human Recombinant His Tag protein encoding 203-317 amino acids.

Source: Escherichia Coli.

Physical Appearance: Sterile lyophilized powder.

Formulation: Each mg contains 1X PBS, 0.1% SDS and 1mM DTT.

CD4 General Information

Application:
Protein Assay, Antibody Production, Western Blotting.

Storage:
Store vial at -20oC to -80oC. When stored at the recommended temperature, this protein is stable for 12 months. Please avoid freeze-thaw cycles.

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