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Bortezomib 5mg

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(N-[1-(Dihydroxyboryl)-3-methylbutyl]-Nα-(2-pyrazinylcarbonyl)phenylalaninamide; Velcade)

Purity > 99.0%

 CAS Number:   179324-69-7
 Chemical Formula:   C19H25BN4O4
 Molecular Weight:   384.24 g/mol


Bortezomib is a highly selective, reversible inhibitor of the 26S proteasome and has shown high antimyeloma activity. Bortezomib caused comparable growth suppression in LNCaP-Pro5 and PC3M-Pro4 cells.

Solubility: Soluble in DMSO at 200 mg/mL; soluble in ethanol at 200 mg/mL; very poorly soluble in water; maximum solubility in plain water is estimated to be about 5-10 µM; buffers, serum, or other additives may increase or decrease the aqueous solubility.

Storage: Store at or below -20 ºC. 

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