Loading... Please wait...(N-[1-(Dihydroxyboryl)-3-methylbutyl]-Nα-(2-pyrazinylcarbonyl)phenylalaninamide; Velcade)
Purity > 98.0%
| CAS Number: | 179324-69-7 |
| Chemical Formula: | C19H25BN4O4 |
| Molecular Weight: | 384.24 g/mol |
Bortezomib is a highly selective, reversible inhibitor of the 26S proteasome and has shown high antimyeloma activity. Bortezomib caused comparable growth suppression in LNCaP-Pro5 and PC3M-Pro4 cells.
Solubility: Soluble in DMSO at 200 mg/mL; soluble in ethanol at 200 mg/mL; very poorly soluble in water; maximum solubility in plain water is estimated to be about 5-10 µM; buffers, serum, or other additives may increase or decrease the aqueous solubility.
Storage: Store at or below -20 ºC.