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Anti-VEGFR2 Monoclonal
| Clone | FLK-6 |
| Size | 100μg/vial |
| Form | lyophilized |
| Ig type | mouse IgG1 |
| Immunogen | Recombinant human extracellular domain of VEGFR-2 (KDR). |
| Application | WB; IHC-F |
| Cross Reactivity | Human. |
| Reconstitution | 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used. |
| The antibody concentration will be 100μg/ml. | |
| Storage | At -20˚C for one year. After reconstitution, at 4˚C for one month. |
| It can also be aliquotted and stored frozen at -20˚C for a longer time. | |
| Avoid repeated freezing and thawing. | |
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VEGF, a homodimeric glycoprotein of relative molecular mass 45,000, is the only mitogen that specifically acts on endothelial cells. The importance of VEGF and its receptor system in tumor growth and intervention in this system may provide promising approaches to cancer therapy. VEGF receptor 2 is a member of a receptor tyrosine kinase family.Like other growth factor receptors, upon ligand binding VEGF receptor 2 dimerises and is autophosphorylated on multiple tyrosine residues. |
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