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Anti-Tau Monoclonal 100ug

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Anti-Tau Monoclonal

Clone TAU-93
Size  100μg/vial
Form lyophilized
Ig type mouse IgG1
Immunogen Bovine microtubule-associated proteins (MAPs).
Application WB; IHC-P
Cross Reactivity Human, mouse, rat.
Reconstitution 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, 
  the antibody concentration will be 100μg/ml.
Storage At -20˚C for one year. After reconstitution, at 4˚C for one month. 
             It can also be aliquotted and stored frozen at -20˚C for a longer time. 
  Avoid repeated freezing and thawing.

The microtubule-associated proteins (MAPs) coassemble with tubulin into microtubules in vitro. Microtubule-associated protein tau appears to be enriched in axons. Tau are composed of 352 to 441 amino acids. The isoforms differ from each other by the presence or absence of 29-amino acid or 58-amino acid inserts located in the N terminus and a 31-amino repeat located in the C terminus. tau is important in establishing and maintaining neuronal morphology and is a major component of the neurofibrillary tangles (NFTs) characteristic of Alzheimer's brain. Microtubule-associated protein tau (MTBT1) is mapped to chromosome 17q21.

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