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Anti-Talin Monoclonal
| Clone | Tal-33 |
| Size | 100μg/vial |
| Form | lyophilized |
| Ig type | mouse IgG1 |
| Immunogen | Purified chicken gizzard talin. |
| Application | WB |
| Cross Reactivity | Human, mouse, rat, chicken, frog. |
| Reconstitution | 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, |
| the antibody concentration will be 100μg/ml. | |
| Storage | At -20˚C for one year. After reconstitution, at 4˚C for one month. |
| It can also be aliquotted and stored frozen at -20˚C for a longer time. | |
| Avoid repeated freezing and thawing. | |
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Talin is a high molecular weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell contacts. Talin serves a function of linking vinculin to the integrins, and, thus, the cytoskeleton to extracellular matrix (ECM) receptors. It has a mass of 270 kD and shares 23% N-terminal identity with ezrin, which has similar functions. TLN gene is mapped to 9p. |
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