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Anti-PCNA Monoclonal 100ug

Price:
$215.00
SKU:
BI-MA1083-100UG
Availability:
Usually Ships within 24 hrs.
Quantity:

Anti-PCNA Monoclonal

Clone IML-83
Size  100μg/vial
Form lyophilized
Ig type mouse IgG2a
Immunogen Protein A fusion protein.
Application WB; IHC-P; IHC-F; ICC
Cross Reactivity Human, mouse, rat.
Reconstitution 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, 
  the antibody concentration will be 100μg/ml.
Storage At -20˚C for one year. After reconstitution, at 4˚C for one month. 
             It can also be aliquotted and stored frozen at -20˚C for a longer time. 
  Avoid repeated freezing and thawing.
   

Proliferating cell nuclear antigen (PCNA) was originally identified by immunofluorescence as a nuclear protein whose appearance correlated with the proliferative state of the cell. PCNA /cyclin has been localized by in situ hybridization to the short arm of human chromosome 20 with a peak of grains over band 20p13. PCNA gene is present in single copy and has 6 exons. It spans 4,961 bp. Synthesis of the nuclear protein cyclin and DNA in quiescent mouse fibroblasts is coordinately induced by serum and purified growth factors. PCNA controls establishment of sister chromatid cohesion during S phase.

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