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Anti-Paxillin Monoclonal 100ug

Price:
$215.00
SKU:
BI-MA1080-100UG
Availability:
Usually Ships within 24 hrs.
Quantity:

Anti-Paxillin Monoclonal

Clone PAX-14
Size  100μg/vial
Form lyophilized
Ig type mouse IgG1
Immunogen C-terminal part of recombinant chicken paxillin (amino acids 305-559).
Application WB; ICC
Cross Reactivity Human, mouse, rat, chicken.
Reconstitution 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used,
  the antibody concentration will be 100μg/ml.
Storage At -20˚C for one year. After reconstitution, at 4˚C for one month. 
             It can also be aliquotted and stored frozen at -20˚C for a longer time. 
  Avoid repeated freezing and thawing.
   

The paxillin gene can be alternatively spliced to include 1 of 2 alternative exons, generating beta and gamma isoforms. Paxillin is a 68-kDa focal adhesion protein that is phosphorylated on tyrosine residues in fibroblasts in response to transformation by v-src, treatment with platelet-derived growth factor, or cross-linking of integrins. The 68-kD protein (paxillin) is a cytoskeletal component that localizes to the focal adhesions at the ends of actin stress fibers in chicken embryo fibroblasts. It is also present in the focal adhesions of Madin-Darby bovine kidney (MDBK) epithelial cells but is absent, like talin, from the cell-cell adherens junctions of these cells.

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