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Anti-Pan-Cadherin Monoclonal 100ug

Price:
$215.00
SKU:
BI-MA1079-100UG
Availability:
Usually Ships within 24 hrs.
Quantity:

Anti-Pan-Cadherin Monoclonal

Clone PC-79
Size  100μg/vial
Form lyophilized
Ig type mouse IgG1
Immunogen Synthetic peptide corresponding to the C-terminal amino acids of chicken N-Cadherin
  with an extra N-terminal lysine residue (24 amino acids) coupled to KLH.
Application WB; IHC-P
Cross Reactivity Human, mouse, rat, rabbit, chicken, snake.
Reconstitution 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, 
  the antibody concentration will be 100μg/ml.
Storage At -20˚C for one year. After reconstitution, at 4˚C for one month. 
             It can also be aliquotted and stored frozen at -20˚C for a longer time. 
  Avoid repeated freezing and thawing.
   

Cadherins are calcium-dependent cell-cell adhesion molecules that mediate cell-cell binding in a homophilic manner. They play an important role in the growth and development of cells via the mechanisms of control of tissue architecture and the maintenance of tissue integrity. Cadherin expression is regulated spatially as well as temporally. Cadherins are thought to play an important role in development and maintenance of tissues through selective cell-cell adhesion activity and may be involved also in the invasion and metastasis of malignant tumors. Cadherin regulates dendritic spine morphogenesis. A cadherin gene cluster is mapped to a region of chromosome 5 subject to frequent allelic loss in carcinoma.

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