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Anti-MMP2 Polyclonal 100ug

Price:
$215.00
SKU:
BI-PA1122-1-100UG
Availability:
Usually Ships within 24 hrs.
Quantity:

Anti-MMP2 Polyclonal

Size  100μg/vial
Form Lyophilized
Ig type Rabbit IgG
Immunogen A synthetic peptide corresponding to a sequence at the C-terminal of human MMP2, identical to the related rat and mouse sequence.
Application WB,ICC,ELISA
Reconstitution Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Storage At -20˚C for one year. After reconstitution, at 4˚C for one month. 
             It can also be aliquotted and stored frozen at -20˚C for a longer time. 
  Avoid repeated freezing and thawing.

Matrix metalloproteinase-2 (MMP2) is a Type IV collagenase, 72-kD, which is also known as gelatinase and is a member of a group of secreted zinc metalloproteases. The MMP2 gene is 17 kb long with 13 exons varying in size from 110 to 901 bp and 12 introns ranging from 175 to 4,350 bp , located within a region of human chromosome 16q13. In addition,The extra exons encode the amino acids of the fibronectin-like domain which has so far been found in only the 72- and 92-kDa type IV collagenase. MMP2,which has a critical role in the binding of progelatinase A and TIMP4 via the C-terminal hemopexin-like domain (C domain), is functionally associated on the surface of angiogenic blood vessels. NOT only is a likely effector of endometrial menstrual breakdown, MMP2 is also effector and regulator of the inflammatory response. Moreover, MMP2 could be helpful in diagnosing Takayasu arteritis.


 

Concentration

Tested Species

Concluded Species

Antigen Retrieval

WB

0.1-0.5μg/ml

Hu

Ms, Rat

-

ICC

1μg/ml

Hu

Ms, Rat

By Heat

ELISA

0.1-0.5μg/ml

Hu

Ms, Rat

-


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