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Anti-MEF2C Polyclonal 100ug

Price:
$215.00
SKU:
BI-PA1824-100UG
Availability:
Usually Ships within 24 hrs.
Quantity:

Anti-MEF2C Polyclonal

Size  100μg/vial
Form Lyophilized
Ig type Rabbit IgG
Immunogen A synthetic peptide corresponding to a sequence at the C-terminal of human MEF2C, identical to the related rat sequence.
Application WB,IHC-P
Reconstitution Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Storage At -20˚C for one year. After reconstitution, at 4˚C for one month. 
             It can also be aliquotted and stored frozen at -20˚C for a longer time. 
  Avoid repeated freezing and thawing.

MEF2C(myocyte enhancer factor 2C) also called MADS box transcription enhancer factor 2, polypeptide C ,is a protein that in humans is encoded by the MEF2C gene. MEF2C is a transcription factor in the Mef2 family.MEF2C, however, is induced late during myogenic differentiation and has a strict tissue-specific pattern of expression not seen in MEF2A or MEF2B. By fluorescence in situ hybridization, the human MEF2C is mapped to chromosome 5q14, a region with homology of synteny to the mouse location.MEF2C may be involved with maintenance of the differentiated state. Both MEF2A and Mef2c programmed similar profiles of gene expression in the heart that included genes involved in extracellular matrix remodeling, ion handling, and metabolism. NCOA2 mediates the coactivation of MEF2C-dependent transcription through interaction with the MADS box domain of MEF2C.


 

Concentration

Tested Species

Concluded Species

Antigen Retrieval

WB

0.1-0.5μg/ml

Hu, Rat

-

-

IHC-P

0.5-1μg/ml

Hu, Rat

-

By Heat


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