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Categories
Anti-Insulin Receptor alpha Polyclonal
| Size | 100μg/vial |
| Form | Lyophilized |
| Ig type | Rabbit IgG |
| Immunogen | A synthetic peptide corresponding to a sequence at the N-terminal of human Insulin Ralpha, identical to the related rat and mouse sequence. |
| Application | WB,IHC-P |
| Reconstitution | Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
| Storage | At -20˚C for one year. After reconstitution, at 4˚C for one month. |
| It can also be aliquotted and stored frozen at -20˚C for a longer time. | |
| Avoid repeated freezing and thawing. | |
|
Insulin receptor is a tetramer of 2 alpha and 2 beta subunits. The alpha and beta subunits are coded by a single gene and are joined by disulfide bonds, a mechanism parallel to that of its ligand, insulin. The insulin receptor has an intrinsic tyrosine kinase activity that is essential for signal transduction. A mutant insulin receptor gene lacking almost the entire kinase domain has been identified in an individual with type A insulin resistance and acanthosis nigricans. |
|
|
Concentration |
Tested Species |
Concluded Species |
Antigen Retrieval |
|
|
WB |
0.1-0.5μg/ml |
Hu, Rat |
Ms |
- |
|
IHC-P |
0.5-1μg/ml |
Dog, Rat |
Ms, Hu |
By Heat |
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