Clone | GEL-42 |
Size | 100μg/vial |
Form | lyophilized |
Ig type | mouse IgG1 |
Immunogen | Human plasma gelsolin. |
Application | WB; IHC-P; IHC-F |
Cross Reactivity | Human, rabbit, bovine. |
Reconstitution | 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used. |
The antibody concentration will be 100μg/ml. | |
Storage | At -20˚C for one year. After reconstitution, at 4˚C for one month. |
It can also be aliquotted and stored frozen at -20˚C for a longer time. | |
Avoid repeated freezing and thawing. | |
Gelsolin, a protein of leukocytes, platelets, and other cells, severs actin filaments in the presence of submicromolar calcium, thereby solating cytoplasmic actin gels. A gelsolin variant with 23 more N-terminal amino acids is a plasma component probably involved in the clearance of actin, the most abundant human protein, from the circulation. Gelsolin is located in 9q34. Plasma and cytoplasmic gelsolins are encoded by a single gene and contain a duplicated actin-binding domain. |