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Anti-Cystatin C Polyclonal 100ug

Price:
$215.00
SKU:
BI-PA1369-100UG
Availability:
Usually Ships within 24 hrs.
Quantity:

Anti-Cystatin C Polyclonal

Size  100μg/vial
Form Lyophilized
Ig type Rabbit IgG
Immunogen A synthetic peptide corresponding to a sequence at the C-terminal of human Cystatin C.
Application WB,IHC-P,ICC
Reconstitution Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Storage At -20˚C for one year. After reconstitution, at 4˚C for one month. 
             It can also be aliquotted and stored frozen at -20˚C for a longer time. 
  Avoid repeated freezing and thawing.

Cystatin C or cystatin 3, a protein encoded by the CST3 gene, is mainly used as a biomarker of kidney function. Recently, it has been studied for its role in predicting new-onset or deteriorating cardiovascular disease. It also seems to play a role in brain disorders involving amyloid, such as Alzheimer's disease. By human-rodent somatic cell hybridizations, Abrahamson et al. (1989) mapped the human CST3 to chromosome 20. Cystatin C was originally described as a constituent of normal cerebrospinal fluid (CSF) and of urine from patients with renal failure (Grubb and Lofberg, 1982). It is present in a number of neuroendocrine cells and its concentration in the CSF was reported to be 5.5 times that in plasma of healthy adults (Lofberg and Grubb, 1979; Lofberg et al., 1981; Lofberg et al., 1983). Grubb and Lofberg (1982) detected the protein in human pituitary gland, and suggested that it is part of the gastroenteropancreatic neuroendocrine system.


 

Concentration

Tested Species

Concluded Species

Antigen Retrieval

WB

0.1-0.5μg/ml

Hu

-

-

IHC-P

0.5-1μg/ml

Hu

-

By Heat

ICC

0.5-1μg/ml

Hu

-

-


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