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Anti-Cyclin D1 Monoclonal 100ug

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Anti-Cyclin D1 Monoclonal

Clone CY-D1
Size  100μg/vial
Form lyophilized
Ig type mouse IgG2a
Immunogen Recombinant human cyclin D1 protein.
Application WB; IHC-P; IHC-F; ICC
Cross Reactivity Human, mouse, rat.
Reconstitution 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used.  
  The antibody concentration will be 100μg/ml.
Storage At -20˚C for one year. After reconstitution, at 4˚C for one month. 
             It can also be aliquotted and stored frozen at -20˚C for a longer time. 
  Avoid repeated freezing and thawing.

D-type cyclins (cyclins D1, D2, and D3) are regarded as essential links between cell environment and the core cell cycle machinery. CyclinD1(CCND1), also known as BCL1. Expression of cyclin D1, but not of cyclins A and E, was induced by transfection of the RB gene into RB-deficient tumor cells. CCND1 gene to 11q13. cyclin D1 gene can function as an oncogene. Cyclin D1 expression is regulated by the retinoblastoma protein.

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