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Anti-Catenin γ (Plakoglobin) Monoclonal 100ug

Price:
$215.00
SKU:
BI-MA1012-100UG
Availability:
Usually Ships within 24 hrs.
Quantity:

Anti-Catenin γ (Plakoglobin) Monoclonal

Clone CN-3
Size  100μg/vial
Form lyophilized
Ig type mouse IgG1
Immunogen Recombinant chicken plakoglobin.
Application WB; IHC-F;ICC
Cross Reactivity Human, rat, chicken.
Reconstitution 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used.  
  The antibody concentration will be 100μg/ml.
Storage At -20˚C for one year. After reconstitution, at 4˚C for one month. 
             It can also be aliquotted and stored frozen at -20˚C for a longer time. 
  Avoid repeated freezing and thawing.
   

Junction Plakoglobin (JUP) ,also knows as catenin gamma, is a major cytoplasmic protein that occurs in a soluble and a membrane-associated form and is the only known constituent common to the submembranous plaques of both kinds of adhering junctions, the desmosomes and the intermediate junctions. It is a component of the cadherin-catenin complex, which is predominantly localized where actin filaments anchor in adherens junctions of epithelial cells. The human plakoglobin gene localizes on chromosome 17q21. Gamma-catenin is regulated by the APC tumor suppressor and its oncogenic activity is distinct from that of beta-catenin.

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