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Anti-CA2 Polyclonal 100ug

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Anti-CA2 Polyclonal

Size  100μg/vial
Form Lyophilized
Ig type Rabbit IgG
Immunogen A synthetic peptide corresponding to a sequence in the middle region of human CA2 , identical to the related mouse and rat sequence.
Application WB
Reconstitution Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Storage At -20˚C for one year. After reconstitution, at 4˚C for one month. 
             It can also be aliquotted and stored frozen at -20˚C for a longer time. 
  Avoid repeated freezing and thawing.

Carbonic anhydrase II (CA2), is one of fourteen forms of human alpha Carbonic anhydrases. Carbonic anhydrases (CAs) are a family of zinc metalloenzymes. Using Southern blot analysis and restriction endonucleases, it is determined that the CA2 gene consists of 7 exons. Using a mouse CA II cDNA hybridization probe with a panel of mouse-human cell hybrids, The CA2 gene was assigned to human chromosome 8. CA2 is expressed at high levels in osteoclasts during bone resorption. It is demonstrated in 2 in vitro culture systems that antisense RNA and DNA blocked expression of CA2 and led to decreased bone resorption. In the choroid plexus, CA2 supports the transport of bicarbonate ions, sodium ions, and water from the blood to the cerebrospinal fluid.



Tested Species

Concluded Species

Antigen Retrieval



Hu, Rat, Ms



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