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Anti-c-Myc Monoclonal 100ug

Price:
$215.00
SKU:
BI-MA1028-100UG
Availability:
Usually Ships within 24 hrs.
Quantity:

Anti-c-Myc Monoclonal

Clone IMD-3
Size  100μg/vial
Form lyophilized
Ig type mouse IgG2a
Immunogen Synthetic peptide corresponding to residues 408-439 of 
                       the human p62c-Myc protein.
Application WB; IHC-P; ICC
Cross Reactivity Human.
Reconstitution 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, 
  the antibody concentration will be 100μg/ml.
Storage At -20˚C for one year. After reconstitution, at 4˚C for one month. 
             It can also be aliquotted and stored frozen at -20˚C for a longer 
  time. Avoid repeated freezing and thawing.
   

C-Myc is an oncogene that functions both in the stimulation of cell proliferation and in apoptosis. c-Myc elicits its oncogenic activity by causing immortalization, and to a lesser extent the transformation of cells, in addition to several other mechanisms. The c-MYC proto-oncogene encodes a transcription factor that is critical for cell growth and proliferation. It is one of the genes frequently altered in cancer cells in which it exhibits constitutive activity. Downregulation of c-Myc is critical for 2-Methoxyestradiol (2ME2)-induced oxidative stress and apoptosis in AML cells. And its up-regulation is important for promoting lymphocyte cell division, and demonstrating that GFP-c-Myc expression is a marker of proliferating lymphocytes in vivo..

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