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Anti-BSEP Polyclonal
| Size | 100μg/vial |
| Form | Lyophilized |
| Ig type | Rabbit IgG |
| Immunogen | A synthetic peptide corresponding to a sequence at the C-terminal of human BSEP, different from the related rat sequence by one amino acid, and from the mouse sequence by three amino acids. |
| Application | WB,IHC-P |
| Reconstitution | Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
| Storage | At -20˚C for one year. After reconstitution, at 4˚C for one month. |
| It can also be aliquotted and stored frozen at -20˚C for a longer time. | |
| Avoid repeated freezing and thawing. | |
|
Bile Salt Export Pump (BSEP) is a protein which in humans is encoded by the ABCB 11 gene. It is a member of the superfamily of ATP-binding cassette (ABC) transporters, also known as ABCB11. It is mapped to chromosome 2q24. The BSEP protein is mainly expressed in the liver. ABCB11 is a gene associated with progressive familial intrahepatic cholestasis type 2 (PFIC2) which caused by mutations in the ABCB11 gene will increases the risk of hepatocellular carcinoma in early life. |
|
|
Concentration |
Tested Species |
Concluded Species |
Antigen Retrieval |
|
|
WB |
0.1-0.5μg/ml |
Hu, Rat |
Ms |
- |
|
IHC-P |
0.5-1μg/ml |
Hu, Rat |
Ms |
By Heat |
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