Loading... Please wait...
  • My Account
  • Order Status
  • Wish Lists

MMP 1, Human


MMP 1, Human

(Interstitial collagenase, Fibroblast collagenase, Matrix metalloproteinase-1, MMP-1, MMP1, CLG, CLGN.)

MMP-1 (interstitial collagenase) can break down a wide range of substrates including types I, II, III, VII, VIII, and X collagens as well as L-Selectin, pro-TNF, IL-1?, IGFBP-3, IGFBP-5, casein, gelatin, ?1 antitrypsin, myelin basic protein, pro-MMP2 and pro-MMP9. A significant function of MMP-1 is the degradation of fibrillar collagens in extracellular matrix remodeling. MMP-1 is expressed in fibroblasts, keratinocytes, endothelial cells, monocytes and macrophages. MMP1 can be divided into a number of distinct domains: a prodomain which is cleaved on activation, a catalytic domain containing the zinc binding site and a short hinge region with a carboxyl terminal domain. MMP1 is part of a cluster of MMP genes which localize to chromosome 11q22.3.

MMP-1 Human Recombinant produced in HEK293 cells is a proform of the Human MMP1 (Met1-Asn469) and fused with a ployhistide tag at the C-terminus, having an Mw of 52kDa. MMP-1 is purified by proprietary chromatographic techniques.

Purity: Greater than 95% as determined by SDS-PAGE.

Source: HEK293 cells.

Physical Appearance: Sterile Filtered colorless solution.

Formulation: The MMP-1 is supplied as a 0.2µm filtered solution in MES, NaCl, Glycerol and Brij35.

MMP 1 General Information

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles.

Free Shipping within the Continental USA

Add to Wish List

Click the button below to add the MMP 1, Human to your wish list.

Let's Stay in Touch

Recently Viewed...

Terms of Service & Privacy Policy | Sitemap | P212121 Company Information

All prices are in USD Copyright 2023 P212121, LLC.