Loading... Please wait...
Categories
Crenolanib
(CP-868596)
Purity > 99.5%
| CAS Number: | 670220-88-9 |
| Chemical Formula: | C26H29N5O2 |
| Molecular Weight: | 443.54 g/mol |
Crenolanib is an orally bioavailable, selective small molecule inhibitor of the Platelet-derived growth factor receptor (PDGFR) tyrosine kinase, inhibiting both purified PDGFRα and PDGFRβ with IC50s of 0.9 nM and 1.8 nM, respectively. It is also a type I pan-FLT3 inhibitor, highly selective over the closely related protein tyrosine kinase KIT, capable of inhibiting both FLT3/ITD and resistance-conferring FLT3/D835 mutants in vivo (Refs 2 & 3). It is considered to be an important next-generation FLT3 inhibitor.
Solubility: Soluble in DMSO, and water with 1 eq. of acid
Store: Store at 0°C (short term), -20°C (long term), desiccated
Free Shipping within the Continental USA
Add to Wish List
Let's Stay in Touch
Recently Viewed...
Terms of Service & Privacy Policy | Sitemap | P212121 Company Information | Accessibility Statement
Products are for research use only and are not intended for human use. We do not sell to patients or the public. Buyers must be employeed by scientific research companies or universities.
WARNING: Products sold can expose you to chemicals including lead, which is known to the State of California to cause cancer, birth defects, and/or other reproductive harm. For more information, go to www.P65Warnings.ca.gov.
All prices are in USD Copyright 2025 P212121, LLC.