Examines a number of factors that influence protein crystallization including precipitating and crosslinking agents. In addition, more than 30 detergents were explored for their ability to prevent sample aggregation and influence crystal growth.
Vergis, J.M.; Purdya, M.D.; Wiener, M.C. A High-Throughput Differential Filtration Assay to Screen and Select Detergents for Membrane Proteins. Analytical Biochemistry. (2010), Vol. 407, Issue 1, 1-11.
Paper discusses the development of an assay that characterizes the stability and size of membrane proteins exchanged into a panel of 94 commercially available and chemically diverse detergents.