Purity >815 μg/mg
CAS Number: | 7240-38-2 |
Chemical Formula: | C19H18N3NaO5S H2O |
Molecular Weight: | 441.45 g/mol |
Oxacillin sodium is a freely soluble (50 mg/mL) narrow spectrum β-lactam antibiotic of the penicillin class. Oxacillin is used primarily against gram positive organisms namely resistant Staphylococcus species.
β-lactams interfere with PBP (penicillin binding protein) activity involved in the final phase of peptidoglycan synthesis. PBP’s are enzymes which catalyze a pentaglycine crosslink between alanine and lysine residues providing additional strength to the cell wall. Without a pentaglycine crosslink, the integrity of the cell wall is severely compromised and ultimately leads to cell lysis and death. Resistance to β-lactams is commonly due to cells containing plasmid encoded β-lactamases. Oxacillin however, is resistant to the degradative effects of β-lactamases.
Appearance: Fine White Crystalline Powder
Melting point: 188 °C (dec)
Store: 2-8 °C
Selleck Chemicals | S2563-200MG |
TCI America | O0353-25G |
TCI America | O0353-5G |
US Pharmacopeia | 1481000 |