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Anti-P-Glycoprotein (MDR) Monoclonal
| Clone | PG-13 |
| Size | 100μg/vial |
| Form | lyophilized |
| Ig type | mouse IgG1 |
| Immunogen | A mixture of human and hamster drug-resistant whole cells and crude plasma membranes. |
| Application | WB; IHC-P; IHC-F; ICC |
| Cross Reactivity | Human. |
| Reconstitution | 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used. |
| The antibody concentration will be 100μg/ml. | |
| Storage | At -20˚C for one year. After reconstitution, at 4˚C for one month. |
| It can also be aliquotted and stored frozen at -20˚C for a longer time. | |
| Avoid repeated freezing and thawing. | |
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P-Glycoprotein, also known as Multidrug Resistance 1 (MDR1), is one of the ATP-binding cassette transporters family. P-glycoprotein-1 is involved in the transport of 3 of these protease inhibitors in vitro. MDR1 gene is mapped to the 7q21.1 by in situ hybridization. The MDR1 gene product, P-glycoprotein, mediates the transport of the cardiac glycoside, digoxin. |
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