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Anti-MCM3 Polyclonal
| Size | 100μg/vial |
| Form | Lyophilized |
| Ig type | Rabbit IgG |
| Immunogen | A synthetic peptide corresponding to a sequence at the N-terminal of human MCM3, identical to the related rat and mouse sequences. |
| Application | WB,IHC-P,ICC |
| Reconstitution | Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
| Storage | At -20˚C for one year. After reconstitution, at 4˚C for one month. |
| It can also be aliquotted and stored frozen at -20˚C for a longer time. | |
| Avoid repeated freezing and thawing. | |
|
MCM3(MINICHROMOSOME MAINTENANCE, S. CEREVISIAE, HOMOLOG OF, 3),also called RLFB or P1 PROTEIN, is a protein that in humans is encoded by the MCM3 gene. MCM3 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The MCM3 gene is mapped to 6p12.2. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. |
|
|
Concentration |
Tested Species |
Concluded Species |
Antigen Retrieval |
|
|
WB |
0.1-0.5μg/ml |
Hu, Rat |
Ms |
- |
|
IHC-P |
0.5-1μg/ml |
Hu, Rat |
Ms |
By Heat |
|
ICC |
0.5-1μg/ml |
Hu |
- |
- |
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