Size | 100μg/vial |
Form | Lyophilized |
Ig type | Rabbit IgG |
Immunogen | A synthetic peptide corresponding to a sequence at the C-terminal of human Canstatin, identical to the related rat and mouse sequences. |
Application | WB,IHC-P,IHC-F,ICC |
Reconstitution | Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
Storage | At -20˚C for one year. After reconstitution, at 4˚C for one month. |
It can also be aliquotted and stored frozen at -20˚C for a longer time. | |
Avoid repeated freezing and thawing. | |
Canstatin, a cleavage product corresponding to the collagen alpha 2(IV) NC1 domain, possesses both anti-angiogenic and anti-tumor cell activity. It inhibits proliferation and migration of endothelial cells, reduces mitochondrial membrane potential, and induces apoptosis. Specifically induces Fas-dependent apoptosis and activates procaspase-8 and -9 activity. Ligand for alphavbeta3 and alphavbeta5 integrins. |
Concentration |
Tested Species |
Concluded Species |
Antigen Retrieval |
|
WB |
0.1-0.5μg/ml |
Hu, Rat |
Ms |
- |
IHC-P |
0.5-1μg/ml |
Hu, Rat, Ms |
- |
By Heat |
IHC-F |
0.5-1μg/ml |
Rat, Ms |
Hu |
- |
ICC |
1μg/ml |
Hu |
- |
- |