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Anti-BIN1 Monoclonal
| Clone | BN-1 |
| Size | 100μg/vial |
| Form | lyophilized |
| Ig type | mouse IgG2b |
| Immunogen | Recombinant polypeptide containing amino acids 189-398 of human Bin1. |
| Application | WB;IHC-F;ICC |
| Cross Reactivity | Human, mouse, rat. |
| Reconstitution | 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used. |
| The antibody concentration will be 100μg/ml. | |
| Storage | At -20˚C for one year. After reconstitution, at 4˚C for one month. |
| It can also be aliquotted and stored frozen at -20˚C for a longer time. | |
| Avoid repeated freezing and thawing. | |
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BIN1 (AMPH2) is a novel human gene product with features of a tumor suppressor protein. BIN1 gene to chromosome 2q14. Loss of BIN1 expression appears to be a frequent aberration in human hepatocellular carcinomas . mutations in BIN1 cause centronuclear myopathy by interfering with remodeling of T tubules and/or endocytic membranes, and that the functional interaction between BIN1 and DNM2 is necessary for normal muscle function and positioning of nuclei. |
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