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Anti-α-Actinin Monoclonal 100ug

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Anti-α-Actinin Monoclonal

Clone SA-20
Size  100μg/vial
Form lyophilized
Ig type mouse IgG1
Immunogen Rabbit skeletal α-actinin
Application WB; IHC-P; IHC-F
Cross Reactivity Human, mouse, rat.
Reconstitution 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used,
  the antibody concentration will be 100μg/ml.
Storage At -20˚C for one year. After reconstitution, at 4˚C for one month. 
             It can also be aliquotted and stored frozen at -20˚C for a longer time. 
  Avoid repeated freezing and thawing.

Alpha-actinin was initially isolated from rabbit skeletal muscle as a factor that induces the gelation of F-actin and promotes the superprecipitation of actomyosin. Alpha actinins are actin-binding proteins that carry out different purposes in different different cell types. In myofibrillar cells, alpha-actinin constitutes a major component of Z-discs in striated muscle and of the functionally analogous dense bodies and dense plaques in smooth muscle. alpha-actinin (alpha A) shares structural homology with spectrin and dystrophin.

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