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Doxorubicin HCl
(Adriamycin)
Purity > 98.0%
USP Grade
| CAS Number: |
25316-40-9
|
| Chemical Formula: |
C27H29NO11 HCl
|
| Molecular Weight: |
579.98 g/mol
|
Doxorubicin HCl is an anthracycline antibiotic and 12-hydroxylated version of daunorubicin that inhibits macromolecular biosynthesis through DNA intercalation.
Doxorubicin stops the development of the topoisomerase II enzyme, which relaxes supercoils in DNA for transcription. Doxorubicin stabilizes the topoisomerase II complex after it has broken the DNA chain for replication, which prevents the DNA double helix from being resealed and thereby inhibits the replication process.
Appearance: Red crystalline powder
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| US Pharmacopeia | 1225703 |
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