Cyclosporin A 100 mg

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Price:

$114.00

SKU:

AM-K983-100MG

Cyclosporin A

(Antibiotic S 7481F1; Cyclosporine)

Purity > 98.5 %

CAS Number:	59865-13-3
Chemical Formula:	C₆₂H₁₁₁N₁₁O₁₂
Molecular Weight:	1202.63 g/mol

Cyclosporin A is a fungal metabolite possessing potent immunosuppressive properties. This antibiotic has the ability to inhibit the T-cell receptor signal transduction pathway via the formation of cyclosporin A−cyclophilin complex that inhibits calcineurin (protein phosphatase 2B). Inhibits nitric oxide synthesis induced by interleukin 1α, lipopolysaccharides and TNFα and can block cytochrome c release from mitochondria.

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