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CHIR99021 2 mg

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CHIR99021

(6-{2-[4-(2,4-Dichloro-phenyl)-5-(4-methyl-1H-imidazol- 2-yl)-pyrimidin-2-ylamino]-ethylamino}-nicotinonitrile)

Purity > 99.0%

 CAS Number:   252917-06-9
 Chemical Formula:   C22H18Cl2N8
 Molecular Weight:   465.34 g/mol

 

CHIR-99021 (CT99021) is a GSK-3α and GSK-3β inhibitor with IC50 of 10 nM and 6.7 nM, respectively.

Solubility: Soluble in DMSO at 25 mg/mL with warming; very poorly soluble in ethanol; very poorly soluble in water; maximum solubility in plain water is estimated to be about 20-40 µM; buffers, serum, or other additives may increase or decrease the aqueous solubility. 

Storage: Store at or below -20 ºC.

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Celebrity Endorsements

Lu, et. al. Neural Stem Cells Derived by Small Molecules Preserve Vision Trans Vis Sci Tech. 2013;2(1):1

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